Fig. 1 · Structure
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Ro 04-5595 hydrochloride
GluN2B Antagonist
Ro 04-5595 hydrochloride is a selective antagonist of the GluN2B subunit of the NMDA receptor, with a Ki value of 31 nM. This compound is utilized in research to investigate the role of GluN2B in various neurological disorders and synaptic transmission processes. Its inhibitory effects on NMDA receptor activity make it a valuable tool for studying excitotoxicity and potential therapeutic strategies for conditions such as depression and neurodegenerative diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 64047-73-0 |
| Applications | GluN2B Antagonist |
| Formula | C19H23Cl2NO2 |
| Molecular Weight | 368.30 |
| SMILES | ClC(C=C1)=CC=C1CCC2C3=CC(O)=C(OC)C=C3CCN2C.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.