Fig. 1 · Structure

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Ro-09-4889

Prodrug

Ro-09-4889 is a prodrug that acts as an inhibitor of dihydropyrimidine dehydrogenase (DPD), exhibiting a dose-dependent effect on its target. This compound is utilized in cancer research to investigate therapeutic strategies and the metabolic pathways involved in tumor progression. Its inhibitory action on DPD makes it a valuable tool for studying pyrimidine metabolism in cancer cells.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 216449-60-4
Applications Prodrug
Formula C15H19N3O6
Molecular Weight 337.33
SMILES
C[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](N2C(N=C(C(C=C)=C2)N)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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