Fig. 1 · Structure
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Ro 13-3978
Antischistosomal Agent
Ro 13-3978 is an orally active antischistosomal agent targeting Schistosoma mansoni. It demonstrates significant in vivo efficacy against both juvenile and adult stages of the parasite, making it a valuable tool for schistosomiasis research. Additionally, Ro 13-3978 inhibits dihydrotestosterone-induced proliferation in androgen-dependent cells. This compound serves as an important reagent for studies focusing on schistosomal infections and associated biological mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 70842-04-5 |
| Applications | Antischistosomal Agent |
| Formula | C12H10F4N2O2 |
| Molecular Weight | 290.22 |
| SMILES | O=C1NC(C(=O)N1C2=CC=C(F)C(=C2)C(F)(F)F)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.