Fig. 1 · Structure
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Ro 17-1812
Anticonvulsant Agent
Ro 17-1812 is a selective partial agonist of the benzodiazepine receptor, demonstrating significant anticonvulsant activity. This compound is primarily utilized in research contexts to explore mechanisms underlying seizure disorders and the therapeutic potential of benzodiazepines in epilepsy. Ro 17-1812's modulatory effects on GABAergic transmission make it a valuable tool for investigating neuropharmacological pathways and related disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 90450-01-4 |
| Applications | Anticonvulsant Agent |
| Formula | C18H16ClN3O3 |
| Molecular Weight | 357.79 |
| SMILES | O=C(OCC1CC1)C2=C(N(C3=CC=CC(Cl)=C3C4=O)C=N2)[C@]5(N4CC5)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.