Ro 31-8220 mesylate

Ro 31-8220 mesylate is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate (PMA, IC50 = 1.35 x 10(-6) M) or diacylglycerols (OAG, diC8) by 95%.
Grouped product items
Product Name Price Stock Qty
Ro 31-8220 mesylate 10mg
$120.00
In stock
Ro 31-8220 mesylate 25mg
$250.00
In stock
Ro 31-8220 mesylate 50mg
$420.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's Ro 31-8220 mesylate has been cited by 1 publications
  • Dao-Lai Zhang, .et al. , eLife, 2018, 7: e33432 PMID: 29393851
  • Biological Activity
    Discription Ro 31-8220 mesylate is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate (PMA, IC50 = 1.35 x 10(-6) M) or diacylglycerols (OAG, diC8) by 95%.
    Targets
    Target Value
    Product Information
    Catalog Num A13514
    Formula C25H23N5O2S.CH3SO3H
    Molecular Weight 553.7
    CAS Number 138489-18-6
    SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N.CS(=O)(=O)O
    Synonyms BIM IX, Bisindolylmaleimide IX (mesylate)
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 85 mg/mL (153.52 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.06 mL 90.3 mL 180.6 mL
    0.5 mM 3.61 mL 18.06 mL 36.12 mL
    1 mM 1.81 mL 9.03 mL 18.06 mL
    5 mM 0.36 mL 1.81 mL 3.61 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy Ro 31-8220 mesylate | Ro 31-8220 mesylate Supplier | purchase Ro 31-8220 mesylate | Ro 31-8220 mesylate cost | Ro 31-8220 mesylate manufacturer | order Ro 31-8220 mesylate | Ro 31-8220 mesylate distributor | buy 138489-18-6 | 138489-18-6 Supplier | purchase 138489-18-6 | 138489-18-6 cost | 138489-18-6 manufacturer | order 138489-18-6 | 138489-18-6 distributor