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Ro 31-8472

ACE Inhibitor

Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor that demonstrates potent inhibition of ACE activity. This compound is a derivative of Cilazapril and is primarily utilized in cardiovascular research to investigate mechanisms of hypertension and heart failure. Its ability to modulate the renin-angiotensin system makes it valuable for studying the therapeutic potential in related pathological conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	144284-57-1
Applications	ACE Inhibitor
Formula	C₂₀H₂₇N₃O₆
Molecular Weight	405.44
SMILES	O=C(O)[C@@H]1CCCN2N1C([C@H](CCC2)N[C@@H](CCC3=CC=C(C=C3)O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.