Fig. 1 · Structure
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Ro 32-7315
TACE Inhibitor
Ro 32-7315 is a selective inhibitor of TNF-α converting enzyme (TACE), which plays a critical role in the processing of pro-inflammatory cytokine TNF-α. This compound has demonstrated significant anti-inflammatory activity, making it valuable for studying the role of TNF-α in various inflammatory diseases. Ro 32-7315 is applicable in research focused on novel therapeutic strategies for conditions such as rheumatoid arthritis, cancer, and other TNF-α-mediated pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 219613-02-2 |
| Applications | TACE Inhibitor |
| Formula | C22H35N3O5S |
| Molecular Weight | 453.60 |
| SMILES | O=C(NN(CC(C)C)S(=O)(C)=O)[C@H](CC(C)C)[C@@H](C(NO)=O)C/C=C/C1=CC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.