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RO-4597014

Glucokinase Inhibitor

RO-4597014 is a selective inhibitor of glucokinase, an important regulator of glucose metabolism. It has demonstrated potential in reducing glucose-stimulated insulin secretion, making it a valuable compound for diabetes research. This reagent can be utilized to investigate the role of glucokinase in metabolic disorders and evaluate therapeutic strategies for diabetes management.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	710321-76-9
Applications	Glucokinase Inhibitor
Formula	C₂₁H₂₆ClN₃O₅S
Molecular Weight	467.97
SMILES	O[C@H](CO)C1=CN=C(NC([C@H](CC2CCCC2)C3=CC(Cl)=C(S(=O)(C)=O)C=C3)=O)C=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.