Fig. 1 · Structure
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Ro 5212773
TAAR1 Antagonist
Ro 5212773 is a selective antagonist of trace amine-associated receptor 1 (TAAR1), exhibiting a Ki value of 0.9 nM for mouse TAAR1, while demonstrating minimal activity against other TAARs. As a G protein-coupled receptor, TAAR1 is involved in mediating the effects of endogenous amino acid metabolites. This reagent is valuable for research applications targeting neuropharmacology and the role of TAAR1 in modulating neurotransmitter systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1110781-88-8 |
| Applications | TAAR1 Antagonist |
| Formula | C20H21F3N2O2 |
| Molecular Weight | 378.39 |
| Synonyms | EPPTB |
| SMILES | O=C(NC1=CC=CC(OCC)=C1)C2=CC=C(N3CCCC3)C(C(F)(F)F)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.