RO-5963

Catalog No.: A18813

MDM2/MDMX inhibitor

RO-5963

RO-5963 Chemical Structure

CAS NO. 1416663-77-8

RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53 with IC50s of ~17 nM and ~24 nM, respectively.

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Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53 with IC50s of ~17 nM and ~24 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.27 mL 96.36 mL 192.72 mL
0.5 mM 3.85 mL 19.27 mL 38.54 mL
1 mM 1.93 mL 9.64 mL 19.27 mL
5 mM 0.39 mL 1.93 mL 3.85 mL

*The above data is based on the productmolecular weight 518.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18813
Actions Inhibitor
M. Wt 518.9
Formula C24H21ClF2N4O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1416663-77-8
Synonyms RO-5963; RO 5963; RO5963;
SMILES O=C(NC(CO)CO)C(N(C(N/C1=C\C2=CNC3=C2C=CC(Cl)=C3C)=O)C1=O)C4=CC=C(F)C(F)=C4

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