Fig. 1 · Structure
Documents & Downloads
Ro 64-6198
Opioid Receptor Agonist
Ro 64-6198 is a selective nonpeptide agonist of the nociceptin/orphanin FQ peptide (NOP) receptor, exhibiting a high affinity with an EC50 value of 25.6 nM. It shows over 100-fold selectivity for the NOP receptor compared to classic opioid receptors. This compound is valuable for research applications related to stress, anxiety, addiction, neuropathic pain, cough modulation, and appetite regulation.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 280783-56-4 |
| Applications | Opioid Receptor Agonist |
| Formula | C26H31N3O |
| Molecular Weight | 401.54 |
| SMILES | O=C1NCN(C2=CC=CC=C2)C13CCN([C@H]4CC[C@]5([H])CCCC6=C5C4=CC=C6)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.