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Ro 64-6198

Catalog No.: A62347
Opioid Receptor Agonist
Ro 64-6198 is a selective nonpeptide agonist of the nociceptin/orphanin FQ peptide (NOP) receptor, exhibiting a high affinity with an EC50 value of 25.6 nM. It shows over 100-fold selectivity for the NOP receptor compared to classic opioid receptors. This compound is valuable for research applications related to stress, anxiety, addiction, neuropathic pain, cough modulation, and appetite regulation.
Ro 64-6198 280783-56-4 Opioid Receptor Agonist
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Size Price Stock Qty
5mg
$220.00
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10mg
$360.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRo 64-6198 is a selective nonpeptide agonist of the nociceptin/orphanin FQ peptide (NOP) receptor, exhibiting a high affinity with an EC50 value of 25.6 nM. It shows over 100-fold selectivity for the NOP receptor compared to classic opioid receptors. This compound is valuable for research applications related to stress, anxiety, addiction, neuropathic pain, cough modulation, and appetite regulation.
Product Information
Catalog NumA62347
FormulaC26H31N3O
Molecular Weight401.54
CAS Number280783-56-4
SMILESO=C1NCN(C2=CC=CC=C2)C13CCN([C@H]4CC[C@]5([H])CCCC6=C5C4=CC=C6)CC3
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GPCR/G Protein > Opioid Receptors