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Ro-65-3479

mGlu2/3 Antagonist

Ro-65-3479 is a selective antagonist of the metabotropic glutamate receptors mGlu2 and mGlu3. This compound effectively inhibits glutamate-induced signaling and modulates calcium channel activity. Ro-65-3479 is of particular interest in the research of disorders associated with glutamatergic dysregulation, including anxiety, schizophrenia, and neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	259134-85-5
Applications	mGlu2/3 Antagonist
Formula	C₈H₁₁NO₅
Molecular Weight	201.18
SMILES	O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])C[C@H]1O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.