Fig. 1 · Structure
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Ro 70‐0004
alpha1A-adrenoceptor Antagonist
Ro 70-0004 is a selective alpha1A-adrenoceptor antagonist, exhibiting a pKi of 8.9. This compound is valuable for research applications related to prostatic hyperplasia, enabling studies on its modulation of receptor activity in this condition. Its specificity for the alpha1A subtype makes it a useful tool for elucidating the role of alpha1A-adrenoceptors in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 186386-21-0 |
| Applications | alpha1A-adrenoceptor Antagonist |
| Formula | C20H24F4N4O3 |
| Molecular Weight | 444.42 |
| Synonyms | RS-100975 |
| SMILES | O=C1NC=C(C)C(N1CCCN2CCN(CC2)C3=CC=C(C=C3OCC(F)(F)F)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.