Fig. 1 · Structure
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RO27-3225 TFA
Melanocortin 4 Receptor Agonist
RO27-3225 TFA is a selective agonist of the melanocortin 4 receptor (MC4R), exhibiting an EC50 of 1 nM for MC4R and 8 nM for MC1R, demonstrating approximately 30-fold selectivity for MC4R over MC3R. This compound is recognized for its neuroprotective and anti-inflammatory properties, making it valuable in research related to metabolic regulation and inflammatory conditions. RO27-3225 TFA is suitable for studies focused on the role of MC4R in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1373926-49-8 |
| Applications | Melanocortin 4 Receptor Agonist |
| Formula | C39H52N12O6.xC2HF3O2 |
| Molecular Weight | 784.91 (free base) |
| SMILES | OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)CC(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.