Ro4368554

Catalog No.: A29952
5-HT6 Antagonist
Ro4368554 is a selective antagonist of the 5-HT6 receptor, demonstrating the ability to penetrate the blood-brain barrier. This compound has shown efficacy in reversing memory deficits induced by scopolamine and tryptophan depletion. Ro4368554 serves as a valuable tool for investigating mechanisms underlying cognitive impairment and potential therapeutic strategies for memory-related disorders.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRo4368554 is a selective antagonist of the 5-HT6 receptor, demonstrating the ability to penetrate the blood-brain barrier. This compound has shown efficacy in reversing memory deficits induced by scopolamine and tryptophan depletion. Ro4368554 serves as a valuable tool for investigating mechanisms underlying cognitive impairment and potential therapeutic strategies for memory-related disorders.
Product Information
Catalog NumA29952
FormulaC19H21N3O2S
Molecular Weight355.45
CAS Number478082-99-4
SMILESO=S(C1=CNC2=C1C=CC=C2N3CCN(C)CC3)(C4=CC=CC=C4)=O
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