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Ro4368554

5-HT6 Antagonist

Ro4368554 is a selective antagonist of the 5-HT6 receptor, demonstrating the ability to penetrate the blood-brain barrier. This compound has shown efficacy in reversing memory deficits induced by scopolamine and tryptophan depletion. Ro4368554 serves as a valuable tool for investigating mechanisms underlying cognitive impairment and potential therapeutic strategies for memory-related disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	478082-99-4
Applications	5-HT6 Antagonist
Formula	C₁₉H₂₁N₃O₂S
Molecular Weight	355.45
SMILES	O=S(C1=CNC2=C1C=CC=C2N3CCN(C)CC3)(C4=CC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.