Fig. 1 · Structure
Documents & Downloads
RO5166017
TAAR1 Agonist
RO5166017 is a potent agonist of the Trace Amine-Associated Receptor 1 (TAAR1) with Ki values of 1.9 nM, 2.7 nM, 31 nM, and 24 nM in mouse, rat, human, and cynomolgus monkey models, respectively. This orally active compound demonstrates cross-species functionality, making it an important tool for investigating TAAR1's role in neuropharmacology and potential therapeutic applications. It is suitable for research focused on the modulation of neurotransmitter systems and the pharmacological exploration of TAAR1-related pathways.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1048346-74-2 |
| Applications | TAAR1 Agonist |
| Formula | C12H17N3O |
| Molecular Weight | 219.29 |
| SMILES | CCN(C1=CC=CC=C1)C[C@@H]2N=C(N)OC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.