Fig. 1 · Structure
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RO6806051
FABP4/FABP5 Dual Inhibitor
RO6806051 is a dual inhibitor of FABP4 and FABP5, demonstrating high specificity with Ki values of 0.011 μM for FABP4 and 0.086 μM for FABP5. This compound effectively modulates lipid metabolism and can play a significant role in studies related to obesity, diabetes, and other inflammation-related diseases. Its selective action provides a valuable tool for investigating the molecular pathways associated with these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1433901-75-7 |
| Applications | FABP4/FABP5 Dual Inhibitor |
| Formula | C21H19ClN6 |
| Molecular Weight | 390.87 |
| SMILES | ClC1=CC2=C(N=C(N3CCCCC3)C(C4=NN=NN4)=C2C5=CC=CC=C5)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.