Rodatristat ethyl

Name: Rodatristat ethyl
Brand: Adooq Bioscience
SKU: A20593
Rating: 5 (288 reviews)

Catalog No.: A20593

TPH1 Inhibitor

Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).

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Rodatristat ethyl 1673571-51-1 TPH1 Inhibitor

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$875.00	In stock
10mg	$1,275.00	In stock
25mg	$2,385.00	In stock
50mg	$3,865.00	In stock
100mg	$6,225.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).

Product Information

Catalog Num	A20593
Formula	C29H31ClF3N5O3
Molecular Weight	590.04
CAS Number	1673571-51-1
SMILES	ClC1=CC(C2=CC=CC=C2)=C([C@@H](OC3=NC(N)=NC(N4CCC5(CN[C@H](C(OCC)=O)C5)CC4)=C3)C(F)(F)F)C=C1
Synonyms	KAR5585, KAR 5585, KAR-5585
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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