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Rofleponide 21-palmitate

Catalog No.: A64799
Glucocorticoid Receptor
Rofleponide 21-palmitate specifically targets the glucocorticoid receptor, acting as a synthetic glucocorticoid. This compound exhibits potent anti-inflammatory and immunosuppressive properties, making it valuable for research in the fields of immunology and endocrinology. Its selective action allows for the study of glucocorticoid signaling pathways and therapeutic applications in conditions such as asthma and autoimmune diseases.
Rofleponide 21-palmitate 144653-57-6 Glucocorticoid Receptor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRofleponide 21-palmitate specifically targets the glucocorticoid receptor, acting as a synthetic glucocorticoid. This compound exhibits potent anti-inflammatory and immunosuppressive properties, making it valuable for research in the fields of immunology and endocrinology. Its selective action allows for the study of glucocorticoid signaling pathways and therapeutic applications in conditions such as asthma and autoimmune diseases.
Product Information
Catalog NumA64799
FormulaC41H64F2O7
Molecular Weight706.94
CAS Number144653-57-6
SMILESCCCCCCCCCCCCCCCC(OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@H](O2)CCC)C)=O)=O
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Endocrinology-Hormones > Glucocorticoid receptors