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Rofleponide

Catalog No.: A64802
Glucocorticoid
Rofleponide is a synthetic glucocorticoid that selectively binds to glucocorticoid receptors, exhibiting a high affinity for rat thymic receptors. This compound demonstrates significant anti-inflammatory activity in various experimental animal models. It is utilized in research to explore therapeutic pathways for inflammation-related conditions and to study glucocorticoid receptor signaling.
Rofleponide 144459-70-1 Glucocorticoid
Grouped product items
Size Price Stock Qty
1mg
$125.00
In stock
5mg
$320.00
In stock
10mg
$470.00
In stock
25mg
$700.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRofleponide is a synthetic glucocorticoid that selectively binds to glucocorticoid receptors, exhibiting a high affinity for rat thymic receptors. This compound demonstrates significant anti-inflammatory activity in various experimental animal models. It is utilized in research to explore therapeutic pathways for inflammation-related conditions and to study glucocorticoid receptor signaling.
Product Information
Catalog NumA64802
FormulaC25H34F2O6
Molecular Weight468.53
CAS Number144459-70-1
SMILESOCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@H](O2)CCC)C)=O
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Endocrinology-Hormones > Glucocorticoid receptors