Roginolisib

Catalog No.: A79784
PI3Kδ Inhibitor
Roginolisib is a selective PI3Kδ inhibitor that exhibits potent activity with an IC50 of 145 nM. This compound demonstrates high selectivity against a broad panel of 278 additional kinases, making it a valuable tool for research in cell signaling pathways. Its application in studies targeting immune responses and cancer biology highlights the importance of PI3Kδ modulation in therapeutic development.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$95.00
In stock
10mg
$160.00
In stock
25mg
$315.00
In stock
50mg
$490.00
In stock
100mg
$760.00
In stock
200mg
$990.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRoginolisib is a selective PI3Kδ inhibitor that exhibits potent activity with an IC50 of 145 nM. This compound demonstrates high selectivity against a broad panel of 278 additional kinases, making it a valuable tool for research in cell signaling pathways. Its application in studies targeting immune responses and cancer biology highlights the importance of PI3Kδ modulation in therapeutic development.
Product Information
Catalog NumA79784
FormulaC26H27FN4O5S
Molecular Weight526.58
CAS Number1305267-37-1
SMILESO=C(C1=NN(C2=CC=C(CN3CCOCC3)C=C2)C(C4=CC=CC(F)=C45)=C1CS5(=O)=O)N6CCOCC6
SynonymsMSC2360844; IOA-244
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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