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Rogletimide

Aromatase Inhibitor

Rogletimide is a potent aromatase inhibitor that functions by blocking the enzymatic conversion of androgens to estrogens. This compound exhibits significant biological activity in reducing estrogen levels, which is critical in the context of hormone-sensitive cancers. Rogletimide is utilized in cancer research to investigate its therapeutic potential and mechanisms of action in the modulation of estrogen-driven tumorigenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	92788-10-8
Applications	Aromatase Inhibitor
Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25
SMILES	O=C1NC(C(CC)(CC1)C2=CC=NC=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.