Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates the endogenous release of parathyroid hormone (PTH) from the parathyroid glands. By modulating calcium homeostasis and enhancing PTH secretion, Ronacaleret is used in the study of postmenopausal osteoporosis and other bone-related metabolic disorders.
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates the endogenous release of parathyroid hormone (PTH) from the parathyroid glands. By modulating calcium homeostasis and enhancing PTH secretion, Ronacaleret is used in the study of postmenopausal osteoporosis and other bone-related metabolic disorders.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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