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ROS1-IN-1

ROS1 Inhibitor

ROS1-IN-1 is a potent and selective inhibitor of the ROS1 kinase, exhibiting an IC50 of 0.097 μM. This compound effectively antagonizes ROS1-mediated signaling pathways, making it a valuable tool for research into oncogenic processes associated with ROS1 mutations. It is suitable for studies investigating cancer cell proliferation, survival, and sensitivity to targeted therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2883232-34-4
Applications	ROS1 Inhibitor
Formula	C₁₇H₁₅ClN₆S
Molecular Weight	370.86
SMILES	CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.