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ROS1-IN-2

ROS1 Inhibitor

ROS1-IN-2 is a potent ROS1 inhibitor that selectively targets the ROS1 kinase, a critical driver in various cancers. This compound demonstrates significant antitumor activity and is valuable for research into ROS1-driven malignancies. It is particularly useful in studies aimed at understanding the mechanisms of resistance and therapeutic efficacy in cancer treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2120337-16-6
Applications	ROS1 Inhibitor
Formula	C₂₉H₃₇ClN₅O₂P
Molecular Weight	554.06
SMILES	ClC(C(NC1=C(P(C)(C)=O)C=CC=C1)=N2)=CN=C2NC3=CC(C)=C(C4CCN(CC)CC4)C5=C3O[C@H](C)C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.