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ROS1-IN-3

ROS1 Inhibitor

ROS1-IN-3 is a potent ROS1 inhibitor designed for targeted research in oncology. This compound selectively inhibits the ROS1 receptor tyrosine kinase, making it relevant for the study of non-small cell lung cancer (NSCLC). Its capability to disrupt ROS1-mediated signaling pathways underscores its potential use in preclinical studies evaluating therapeutic strategies for NSCLC.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2644645-39-4
Applications	ROS1 Inhibitor
Formula	C₂₀H₁₆FN₇O₃
Molecular Weight	421.38
SMILES	N#CC1=NN2C=CC3=NC2=C1C(NC4(COC5=NC=C(C=C5[C@H]6CCON36)F)CC4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.