World Leading Inhibitor Supplier

France
  • Toll Free 866-930-6790
Trusted by 10,000+ Scientists since 2006

Roscovitine (Seliciclib)

ON SALE

CDK Inhibitor

0 Customer Reviews
Catalog No. A10806

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Roscovitine 10mg A10806-10

Regular Price: €76.00

Special Price: €68.40

Roscovitine 50mg A10806-50

Regular Price: €142.50

Special Price: €128.25

Roscovitine 100mg A10806-100

Regular Price: €190.00

Special Price: €171.00

Roscovitine 200mg A10806-200

Regular Price: €342.00

Special Price: €307.80

Roscovitine (Seliciclib) 10mM * 1mL in DMSO A10806-10mM-D

Regular Price: €82.65

Special Price: €74.39

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Roscovitine (Seliciclib) is a CDK inhibitor that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9.

Roscovitine (Seliciclib)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
Roscovitine (Seliciclib) Citations (1)
  • Vimal Pandey, .et al. Roscovitine effectively enhances antitumor activity of temozolomide in vitro and in vivo mediated by increased autophagy and Caspase-3 dependent apoptosis, Scientific Reports, 2019, 9, Article number: 5012

Chemical Information

Catalog Num A10806
Actions Inhibitor
M. Wt 354.5
Formula C19H26N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 186692-46-6
Synonyms CYC202, Seliciclib
SMILES CC[[email protected]](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C

Biological Activity

Description
 Roscovitine (Seliciclib) is a CDK inhibitor that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9.
Targets
Target Value
CDK5/p35IC50: 0.16μM
Cdc2/CyclinBIC50: 0.65μM
CDK2/CyclinAIC50: 0.7μM
CDK2/CyclinEIC50: 0.7μM
ERK2IC50: 14μM
GST-ERK1IC50: 30μM
ERK1IC50: 34μM
CDK4/CyclinD1IC50: >100μM
CDK6/CyclinD3IC50: >100μM
PKCαIC50: >100μM
PKCβ1IC50: >100μM
PKCβ2IC50: >100μM
PKCγIC50: 100μM
PKCεIC50: >100μM
PKCηIC50: >100μM
c-SrcIC50: 250μM
PKCδIC50: >1000μM
PKCζIC50: >1000μM
v-AblIC50: >1000μM

Solubility

Solubility (25°C) * In vitro DMSO 71 mg/mL (200.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL (16.92 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.21 mL 141.04 mL 282.09mL
0.5 mM 5.64 mL 28.21 mL 56.42 mL
1 mM 2.82 mL 14.1 mL 28.21 mL
5 mM 0.56 mL 2.82 mL 5.64 mL

*The above data is based on the productmolecular weight 354.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Be the first to review this product

Similar product(s)


Keywords:buy Roscovitine (Seliciclib) | Roscovitine (Seliciclib) Supplier | purchase Roscovitine (Seliciclib) | Roscovitine (Seliciclib) cost | Roscovitine (Seliciclib) manufacturer | order Roscovitine (Seliciclib) | Roscovitine (Seliciclib) distributor | buy 186692-46-6 | 186692-46-6 Supplier | purchase 186692-46-6 | 186692-46-6 cost | 186692-46-6 manufacturer | order 186692-46-6 | 186692-46-6 distributor

Receive our newsletter

To keep up to date with the latest products, news from us. We only send a few emails a year and you can unsubscribe at any time.

We Using Safe Payments:
© 2006-2018 AdooQ BioScience. All Rights Reserved.