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Roseltide rT1

Elastase Inhibitor

Roseltide rT1 is a selective inhibitor of neutrophil elastase, exhibiting an IC50 value of 0.47 μM. This compound is part of the Roseltide family (rT1-rT8) and demonstrates the ability to enhance cAMP accumulation in vitro when stimulated by neutrophil elastase. Due to its specific action on elastase, Roseltide rT1 is a valuable tool for research into diseases associated with elastase activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2206692-95-5
Applications	Elastase Inhibitor
Formula	C₁₁₀H₁₇₇N₃₁O₃₁S₆
Molecular Weight	2622.16
SMILES	O=C1N2[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@]3(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@]4(C(=O)N[C@@](CSSC[C@H](N)C(=O)N[C@]1([C@H](CC)C)[H])(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N5[C@@](CCC5)(C(=O)NCC(=O)N[C@@](CSSC3)(C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N[C@H](C(O)=O)C)=O)CSSC4)[H])[H])[H])[H])[H])[H])[H])[H])(CCC2)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.