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Rosuvastatin-d6

Stable Isotope

Rosuvastatin-d6 is a deuterium-labeled derivative of Rosuvastatin, a competitive inhibitor of HMG-CoA reductase with an IC50 of 11 nM. This reagent serves as a stable isotope for metabolic studies, allowing for detailed quantification and tracking of Rosuvastatin’s pharmacokinetics. Rosuvastatin is known to effectively reduce low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels, while also influencing cardiac repolarization dynamics through its interaction with hERG channels. This compound is applicable in research focusing on lipid metabolism and cardiovascular pharmacology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2070009-40-2
Applications	Stable Isotope
Formula	C₂₂H₂₂D₆FN₃O₆S
Molecular Weight	487.57
Synonyms	ZD 4522-d6
SMILES	OC(C[C@H](O)C[C@H](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(C)(=O)=O)N=C1C2=CC=C(C=C2)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.