Rottlerin

Catalog No.: A20743
PKC inhibitor
Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM.
Grouped product items
Product Name Price Stock Qty
Rottlerin 10mg
$54.00
In stock
Rottlerin 25mg
$108.00
In stock
Rottlerin 50mg
$186.00
In stock
Rottlerin 100mg
$318.00
In stock
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Biological Activity
Discription Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM.
Targets
Target Value
Product Information
Catalog Num A20743
Formula C30H28O8
Molecular Weight 516.54
CAS Number CAS: 82-08-6
SMILES O=C(C1=C2C(C=CC(C)(C)O2)=C(O)C(CC3=C(O)C(C)=C(O)C(C(C)=O)=C3O)=C1O)/C=C/C4=CC=CC=C4
Synonyms Mallotoxin; NSC 56346, NSC56346, NSC-56346; NSC 94525, NSC94525, NSC-94525
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 11 mg/mL (21.29 mM)
Water <1 mg/mL
Ethanol 1 mg/mL (1.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.36 mL 96.8 mL 193.6 mL
0.5 mM 3.87 mL 19.36 mL 38.72 mL
1 mM 1.94 mL 9.68 mL 19.36 mL
5 mM 0.39 mL 1.94 mL 3.87 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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