Rotundine

Catalog No.: A11998

Rotundine

Rotundine Chemical Structure

CAS NO. 483-14-7

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

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25 mg

Regular Price: $40.00

Special Price $32.00

50 mg

Regular Price: $60.00

Special Price $48.00

100 mg

Regular Price: $100.00

Special Price $80.00

250 mg

Regular Price: $200.00

Special Price $160.00

10mM * 1mL in DMSO

Regular Price: $65.00

Special Price $52.00

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Biological Activity

Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
Targets
D1 receptor 5-HT1A D2 receptor D3 receptor
166 nM347 nM1.47 μM3.25 μM
In vitro DMSO 8 mg/mL (22.5 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.13 mL 140.67 mL 281.35 mL
0.5 mM 5.63 mL 28.13 mL 56.27 mL
1 mM 2.81 mL 14.07 mL 28.13 mL
5 mM 0.56 mL 2.81 mL 5.63 mL

*The above data is based on the productmolecular weight 355.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11998
CAS No. 483-14-7
Formula C21H25NO4
M. Wt 355.43
Purity >98%
SMILES COC1=C(C2=C(C[[email protected]]3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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