Fig. 1 · Structure

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Rovanersen

Antisense Oligonucleotide

Rovanersen is an antisense oligonucleotide designed to selectively target mutated mRNA transcripts of the huntingtin (HTT) gene, while sparing the normal mRNA. This specificity helps to inhibit the production of the abnormal Huntingtin protein, which is implicated in Huntington's disease pathology. Rovanersen is valuable for research related to Huntington’s disease and for investigating therapeutic strategies aimed at reducing the detrimental effects of mutant HTT expression.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2072901-32-5
Applications Antisense Oligonucleotide
Molecular Weight 6617.00
Synonyms WVE-120101

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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