Fig. 1 · Structure
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Roxatidine
H2 Receptor Antagonist
Roxatidine is an orally active histamine H2-receptor antagonist that exerts its effects by inhibiting proton secretion through the suppression of histamine release. Additionally, Roxatidine reduces the production of VEGF-1, a key factor in inflammation and angiogenesis, highlighting its anti-inflammatory properties. This compound is primarily utilized in research focused on gastric and duodenal ulcers.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 78273-80-0 |
| Applications | H2 Receptor Antagonist |
| Formula | C17H26N2O3 |
| Molecular Weight | 306.41 |
| SMILES | O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.