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RPR-101511

PDGF Inhibitor

RPR-101511 is a 3-substituted quinoline derivative acting as a potent inhibitor of platelet-derived growth factor (PDGF) receptor tyrosine kinase, with an IC50 range of 0.001-0.02 μM. This compound demonstrates key biological activity in the modulation of cell proliferation, differentiation, and survival that are mediated by PDGF signaling pathways. RPR-101511 is suitable for research applications focused on cellular processes influenced by PDGF, particularly in the context of cancer and fibrotic diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	146535-06-0
Applications	PDGF Inhibitor
Formula	C₁₅H₁₃NO₂S
Molecular Weight	271.33
SMILES	COC1=CC2=CC(C3=CSC=C3)=CN=C2C=C1OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.