Fig. 1 · Structure
Documents & Downloads
RS-102221
5-HT2C Receptor Antagonist
RS-102221 is a selective antagonist of the 5-HT2C receptor, exhibiting a Ki value of 10 nM. This compound demonstrates significant selectivity, being nearly 100-fold more effective against the 5-HT2C receptor compared to the 5-HT2A and 5-HT2B receptors. RS-102221 has been shown to promote the differentiation of new nerve cells and is associated with increased food intake and weight gain in rat models, making it a valuable tool for research in neurobiology and metabolic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 185376-97-0 |
| Applications | 5-HT2C Receptor Antagonist |
| Formula | C27H31F3N4O7S |
| Molecular Weight | 612.62 |
| SMILES | O=S(C1=CC=C(C(F)(F)F)C=C1)(NC2=CC(C(CCCCN(CC3)CCC3(NC(N4)=O)C4=O)=O)=C(OC)C=C2OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.