Fig. 1 · Structure
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(RS)-PPG
mGluR Agonist
(RS)-PPG is a selective agonist for group III metabotropic glutamate receptors (mGluRs), exhibiting potent activity with EC50 values of 5.2 μM for hmGluR4a, 4.7 μM for hmGluR6, 185 μM for hmGluR7b, and 0.2 μM for hmGluR8a. This compound demonstrates significant anticonvulsive and neuroprotective effects, making it a valuable tool in neurological research. Its ability to modulate mGluR activity positions (RS)-PPG for potential applications in studying various neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 120667-15-4 |
| Applications | mGluR Agonist |
| Formula | C8H10NO5P |
| Molecular Weight | 231.14 |
| SMILES | O=C(O)C(N)C1=CC=C(P(O)(O)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.