Fig. 1 · Structure
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RSK2-IN-4
RSK2 Inhibitor
RSK2-IN-4 is a selective RSK2 inhibitor that demonstrates an inhibition rate of 13.73% at a concentration of 10 μM. This compound targets the ATP-binding site within the N-terminal kinase domain of RSK2, with the electron-donating group positioned at the 4-position of the phenyl ring playing a critical role in its inhibitory efficacy. RSK2-IN-4 serves as a valuable tool for researchers investigating RSK2's role in signaling pathways and its implications in various cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 62001-32-5 |
| Applications | RSK2 Inhibitor |
| Formula | C13H11ClN4 |
| Molecular Weight | 258.71 |
| SMILES | ClC1=CC=C(NCN2N=NC3=C2C=CC=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.