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RSK2-IN-6

Ribosomal S6 Kinase Inhibitor

RSK2-IN-6 is a selective inhibitor of p90 ribosomal S6 kinase 2 (RSK2), demonstrating a Kd of 856 nM. This compound exhibits significant antitumor activity, particularly against breast cancer and melanoma cell lines, making it a valuable tool for cancer research. Its potential to modulate RSK2 activity highlights its relevance in studies aimed at understanding tumor biology and developing targeted therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	304474-86-0
Applications	Ribosomal S6 Kinase Inhibitor
Formula	C₁₇H₁₅N₅O₃S
Molecular Weight	369.40
SMILES	O=C(C1=CC=CC([N+]([O-])=O)=C1)NNC2=C3C(CCCC4)=C4SC3=NC=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.