Biological Activity
RTC-5 is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.57 mL | 97.86 mL | 195.71 mL |
0.5 mM | 3.91 mL | 19.57 mL | 39.14 mL |
1 mM | 1.96 mL | 9.79 mL | 19.57 mL |
5 mM | 0.39 mL | 1.96 mL | 3.91 mL |
*The above data is based on the productmolecular weight 510.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A19067 |
---|---|
CAS No. | 1423077-49-9 |
Formula | C24H22ClF3N2O3S |
M. Wt | 510.96 |
Purity | >98% |
Synonyms | RTC5, RTC 5 |
SMILES | O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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