Fig. 1 · Structure
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RTC14
Read-Through Compound
RTC14 is a read-through compound that facilitates ribosomal bypass of nonsense mutations in mRNA, enabling the synthesis of full-length, functional proteins. This compound holds promise for research applications targeting various genetic disorders associated with nonsense mutations, including those affecting the ataxia-telangiectasia mutated (ATM) gene and the dystrophin gene. RTC14 may serve as a valuable tool in understanding and potentially treating conditions linked to these mutations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 414909-09-4 |
| Applications | Read-Through Compound |
| Formula | C17H18N2O3 |
| Molecular Weight | 298.34 |
| SMILES | OC1=CC=C(C=C1/N=C/C2=CC=CC([N+]([O-])=O)=C2)C(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.