RTICBM-189 is a potent allosteric modulator of the cannabinoid type-1 (CB1) receptor, demonstrating a pIC50 of 7.54 in Ca2+ mobilization assays. This compound exhibits selective activity with pIC50 values of 5.29 for human CB1 and 6.25 for mouse CB1. RTICBM-189 significantly reduces reinstatement of drug-seeking behavior in rodent models, making it valuable for research on addiction and related neurological disorders.
RTICBM-189 is a potent allosteric modulator of the cannabinoid type-1 (CB1) receptor, demonstrating a pIC50 of 7.54 in Ca2+ mobilization assays. This compound exhibits selective activity with pIC50 values of 5.29 for human CB1 and 6.25 for mouse CB1. RTICBM-189 significantly reduces reinstatement of drug-seeking behavior in rodent models, making it valuable for research on addiction and related neurological disorders.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
