RU-301

Catalog No.: A19156

pan-TAM receptor inhibitor

RU-301

RU-301 Chemical Structure

CAS NO. 1110873-99-8

RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively.

Availability: In stock

Package Price Qty
1 mg
$110.00
5 mg
$320.00
10 mg
$500.00
50 mg
$1,500.00
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Biological Activity

RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively.
In vitro DMSO 84 mg/mL (174.83 mM)
Water Insoluble
Ethanol 2 mg/mL (4.16 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.07 mL 208.13 mL
0.5 mM 4.16 mL 20.81 mL 41.63 mL
1 mM 2.08 mL 10.41 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19156
Actions Inhibitor
CAS No. 1110873-99-8
Formula C21H19F3N4O4S
M. Wt 480.46
Purity >98%
Synonyms RU 301; RU301
SMILES O=C(NCCNC1=CC=C(C(F)(F)F)C=C1[N+]([O-])=O)C2=CC=CC=C2SCC3=CC(C)=NO3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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