Fig. 1 · Structure
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Runx1-CBFβ interaction inhibitor 1
Runx1-CBFβ Inhibitor
Runx1-CBFβ Interaction Inhibitor 1 is an allosteric inhibitor that targets the interaction between the Runt domain and CBFβ, exhibiting an IC50 of 3.2 μM. This compound is instrumental in studying the regulatory mechanisms of hematopoiesis and the role of Runx1 in cancer biology. Its inhibition of the Runx1-CBFβ interaction makes it a valuable tool for researchers investigating transcriptional regulation and related signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 493028-20-9 |
| Applications | Runx1-CBFβ Inhibitor |
| Formula | C12H14N2OS |
| Molecular Weight | 234.32 |
| SMILES | COC(C=C1)=CC=C1C2=C(CC)SC(N)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.