Fig. 1 · Structure
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RUVBL1/2 ATPase-IN-1
Anti-cancer Agent
RUVBL1/2 ATPase-IN-1 is a selective inhibitor of RUVBL1 and RUVBL2 ATPases, exhibiting IC50 values of 6.0 μM and 7.7 μM, respectively. These highly conserved AAA ATPases play significant roles in various cellular processes and are implicated in cancer progression. This compound is essential for research applications focused on understanding cancer mechanisms and developing potential anti-cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 423128-55-6 |
| Applications | Anti-cancer Agent |
| Formula | C28H28F3N5O |
| Molecular Weight | 507.55 |
| SMILES | O=C(C1=C2N=C(C)C(CC3=CC=C(C)C=C3)=C(C)N2N=C1)N4CCN(C5=CC=CC(C(F)(F)F)=C5)CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.