RV-1729 is a potent inhibitor of phosphatidylinositol 3-kinase-delta (PI3Kδ), with an IC50 value of 12 nM for the release of phosphatidylinositol 3,4,5-triphosphate (PIP3). This compound exhibits significant selectivity, being twice as selective for PI3Kδ compared to PI3Kγ and 16 times more selective for PI3Kα. RV-1729 modulates immune and inflammatory responses, making it a valuable tool in research applications related to asthma and chronic obstructive pulmonary disease (COPD).
RV-1729 is a potent inhibitor of phosphatidylinositol 3-kinase-delta (PI3Kδ), with an IC50 value of 12 nM for the release of phosphatidylinositol 3,4,5-triphosphate (PIP3). This compound exhibits significant selectivity, being twice as selective for PI3Kδ compared to PI3Kγ and 16 times more selective for PI3Kα. RV-1729 modulates immune and inflammatory responses, making it a valuable tool in research applications related to asthma and chronic obstructive pulmonary disease (COPD).
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