Apabetalone (RVX-208)

Catalog No.: A13956
BET bromodomain inhibitor
RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 uM for BD2, about 170-fold selectivity over BD1.
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Product Name Price Stock Qty
Apabetalone (RVX-208) 10mg
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Apabetalone (RVX-208) 25mg
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Apabetalone (RVX-208) 50mg
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Apabetalone (RVX-208) 10mM * 1mL in DMSO
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Biological Activity
Discription RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 uM for BD2, about 170-fold selectivity over BD1.
Target Value
Product Information
Catalog Num A13956
Formula C20H22N2O5
Molecular Weight 370.4
CAS Number 1044870-39-4
Synonyms RVX-000222

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 63 mg/mL (170.08 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC Na (1N HCl, PH 2.5-3.0) 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27 mL 134.99 mL 269.98 mL
0.5 mM 5.4 mL 27 mL 54 mL
1 mM 2.7 mL 13.5 mL 27 mL
5 mM 0.54 mL 2.7 mL 5.4 mL
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