Fig. 1 · Structure
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RWJ-676070
Vasopressin antagoni
RWJ-676070 is a dual antagonist of vasopressin V1A and V2 receptors, exhibiting Ki values of 1.4 nM and 14 nM, respectively. This compound is instrumental in research focused on vasopressin signaling pathways and related physiological processes. It may be utilized to investigate potential therapeutic applications in disorders associated with vasopressin dysregulation, such as heart failure and hyponatremia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 813426-25-4 |
| Applications | Vasopressin antagoni |
| Formula | C30H26ClFN2O5 |
| Molecular Weight | 548.99 |
| SMILES | O=C(C(CC1)=C[C@@]21CCN(C(C3=CC=C(NC(C4=CC(F)=CC=C4Cl)=O)C(OC)=C3)=O)C5=CC=CC=C5C2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.