Fig. 1 · Structure
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RX 801077 hydrochloride
I2R Agonist
RX 801077 hydrochloride is a selective agonist of the imidazoline I2 receptor (I2R), exhibiting a Ki value of 70.1 nM. This compound demonstrates significant anti-inflammatory and neuroprotective properties, making it relevant for studies focused on traumatic brain injury (TBI). RX 801077 hydrochloride serves as a valuable tool for investigating the therapeutic potential of I2R activation in neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 89196-95-2 |
| Applications | I2R Agonist |
| Formula | C11H11ClN2O |
| Molecular Weight | 222.67 |
| Synonyms | 2 BFI |
| SMILES | Cl[H].C1(C2=CC3=CC=CC=C3O2)=NCCN1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.