Fig. 1 · Structure
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RX 801077
I2R Agonist
RX 801077 is a selective imidazoline I2 receptor (I2R) agonist with a binding affinity (Ki) of 70.1 nM. This compound exhibits significant anti-inflammatory and neuroprotective properties, making it a valuable tool in research related to traumatic brain injury (TBI). Its selective mechanism of action on the I2R highlights its potential in studying neurodegenerative conditions and inflammation-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 72583-92-7 |
| Applications | I2R Agonist |
| Formula | C11H10N2O |
| Molecular Weight | 186.21 |
| Synonyms | 2 BFI free base |
| SMILES | C1(C2=CC3=CC=CC=C3O2)=NCCN1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.