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RY764

MC4R Agonist

RY764 is a selective agonist for the melanocortin-4 receptor (MC4R), demonstrating an EC50 of 10 nM. This compound effectively reduces food intake and mitigates body weight gain in diet-induced obese (DIO) rat models. RY764 is suitable for research applications focusing on obesity and metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	491845-95-5
Applications	MC4R Agonist
Formula	C₃₄H₅₁FN₄O₃
Molecular Weight	582.79
SMILES	CC(C)(C)NC(C1(C2CCCCC2)CCN(CC1)C([C@H](NC([C@H]3[C@]4([H])N(C[C@](CC4)([H])C3)C)=O)CC5=CC=C(C=C5)F)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.